Tumor-Associated Glaucoma

  • Reena Garg
  • Annapurna Singh
  • Arun D. Singh


Elevation of intraocular pressure (IOP) and glaucoma can be caused by intraocular tumors, which can be primary or metastatic. The risk of glaucoma is determined by the tumor type and location. Both closed- and open-angle glaucoma can occur. Glaucoma is estimated to occur in approximately 3–7.5% of patients with intraocular tumors. Any patient with unilateral elevation of IOP should raise suspicion for glaucoma secondary to intraocular malignancy. Even after successful tumor ablation, glaucoma and its deleterious effects persist. Glaucoma secondary to intraocular tumors often poses difficult management issues both in the short and long term. It is important to recognize glaucoma as a sight-threatening complication of intraocular tumors in both adults and children.


Glaucoma Secondary glaucoma Phakomatoses Neovascular glaucoma Angle seeding Medulloepithelioma Uveal melanoma 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Reena Garg
    • 1
  • Annapurna Singh
    • 2
  • Arun D. Singh
    • 3
  1. 1.Department of OphthalmologyEmory University HospitalAtlantaUSA
  2. 2.Cole Eye Institute, Cleveland ClinicClevelandUSA
  3. 3.Department of Ophthalmic OncologyCole Eye Institute, Cleveland ClinicClevelandUSA

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