Phytochemical Constituents and Pharmacological Effects of Licorice: A Review

  • Nazim A. MamedovEmail author
  • Dilfuza Egamberdieva


Licorice (or “liquorice”) is one of most widely used in foods, herbal medicine, and extensively researched medicinal plants of the world. In traditional medicine licorice roots have been used against treating many ailments including lung diseases, arthritis, kidney diseases, eczema, heart diseases, gastric ulcer, low blood pressure, allergies, liver toxicity, and certain microbial infections. Licorice extract contains sugars, starch, bitters, resins, essential oils, tannins, inorganic salts, and low levels of nitrogenous constituents such as proteins, individual amino acids, and nucleic acids. A large number of biological active compounds have been isolated from Glycyrrhiza species, where triterpene saponins and flavonoids are the main constitutes which show broad biological activity. This review examines recent studies on the phytochemical and pharmacological data and describes some side effects and toxicity of licorice and its bioactive components.


Licorice Glycyrrhiza Traditional medicine Phytochemical constituents 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Medicinal Plants Program, Stockbridge School of AgricultureUniversity of Massachusetts at AmherstAmherstUSA
  2. 2.Faculty of Biology and Soil SciencesNational University of UzbekistanTashkentUzbekistan

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