Newest Antithrombotic Agents: Uses, Challenges, and Reversal Strategies for Surgical Procedures

  • Eisha Wali
  • Sandeep NathanEmail author
Part of the Difficult Decisions in Surgery: An Evidence-Based Approach book series (DDSURGERY)


Management of antiplatelet and anticoagulant agents in patients requiring surgical intervention presents a unique challenge. Relative risks of bleeding and thromboembolism must be carefully assessed and readdressed at regular intervals. In the event of major bleeding complications, targeted transfusions and reversal may be required. This review offers an updated understanding regarding currently available agents, optimal timing and duration of therapy, perioperative management, and reversal strategies.


Antithrombotics Antiplatelets Anticoagulation Bleeding 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of MedicineUniversity of Chicago MedicineChicagoUSA
  2. 2.Section of CardiologyUniversity of Chicago MedicineChicagoUSA

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