PET/CT in Pediatric Oncology

  • Lisa J. States
  • Stephan D. VossEmail author
Part of the Pediatric Oncology book series (PEDIATRICO)


In pediatric practice, 18F-FDG PET/CT is now considered standard of care for the diagnosis, staging, and posttreatment response assessment for an increasing number of pediatric malignancies. The relative rarity of pediatric tumors, availability of PET/CT scanners, and development of pediatric-specific protocols have contributed to the slower standardization of PET/CT practices in the pediatric population as compared to adults. Other pediatric-specific challenges, including radiation concerns, use of IV contrast, and requirements for anesthesia, must also be addressed. This chapter will focus on the use of 18F-FDG PET/CT, protocol options, and normal variations in the pediatric patients, in addition to reviewing the evidence-based literature for specific pediatric cancer types and tumor-like non-cancerous lesions. Recent advances in hybrid PET technology are also presented, with an emphasis on the role these technologies play in driving development of molecular imaging techniques and their application to personalized and targeted approaches to pediatric cancer care.




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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of RadiologyThe Children’s Hospital of Philadelphia (CHOP), Perelman School of Medicine, University of PennsylvaniaPhiladelphiaUSA
  2. 2.Department of RadiologyBoston Children’s Hospital, Harvard Medical SchoolBostonUSA

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