Non-neurologic Late Effects of Therapy

  • Sue C. KasteEmail author
  • Anurag Arora
Part of the Pediatric Oncology book series (PEDIATRICO)


With the overall 5-year survival of patients diagnosed with cancer during childhood and adolescence now exceeding 80%, these survivors represent a rapidly growing population who may be burdened with adverse late toxicities and chronic disease. The chapter is organized by organ systems involved and addresses many of the more common adverse non-neurologic treatment-related late effects. The mechanisms of and risk factors for their development and imaging methods for their detection are discussed.


Survivors of childhood cancer Late effects of cancer therapy Pediatric oncology Oncologic toxicities Chemotherapy Radiation therapy 



The authors are grateful to Vella Laws-Bell for manuscript preparation and to Cynthia Lyle for critical review.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of OncologySt. Jude Children’s Research HospitalMemphisUSA
  2. 2.Department of Diagnostic ImagingSt. Jude Children’s Research HospitalMemphisUSA
  3. 3.Department of RadiologyUniversity of Tennessee Health Science CenterMemphisUSA

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