Relapsing polychondritis (RP) is an uncommon disorder of unknown aetiology which is at the crossroad between auto-inflammatory and autoimmune diseases. It is characterised by recurrent inflammation of cartilaginous structures throughout the body especially of the ears, nose, eyes and tracheobronchial tree. It was described by Jaksch-Wartenhorst as a polychondropathia in 1923 while Pearson et al. coined the term RP in 1960. It has a variety of clinical manifestations affecting many organs and systems, including joints, heart, kidney, skin and others. RP may occur alone and then it is described as primary or can be associated with other conditions characterised as secondary RP.
References and Further Reading
- Banno T, Togawa D, Hasegawa T, Yamato Y, Yoshida G, Kobayashi S, Yasuda T, Arima H, Oe S, Mihara Y, Ushirozako H, Matsuyama Y. The controlled study of diffuse idiopathic skeletal hyperostosis for the assessment of physical function in elderly populations. J Orthop Sci. 2018. pii: S0949-2658(18)30215-X; https://doi.org/10.1016/j.jos.2018.07.017. Epub ahead of print.CrossRefGoogle Scholar