Abstract
Hepatitis B virus (HBV) is a hepatotropic virus that causes systemic infection, predominantly affecting the liver. The viral life cycle of HBV is known well enough that it is possible to control the viral replication with the specific antivirals. However, there is no cure yet for HBV infections. It is a major health problem since more than 2 billion people have been infected with HBV, globally. The spectrum of illness varies from acute hepatitis to chronic hepatitis which may lead to cirrhosis and/or hepatocellular carcinoma. The clinical phases of acute hepatitis B infections range from asymptomatic hepatitis to icteric and fulminant hepatitis. Acute viral hepatitis is usually self-limiting, especially in older than 5-year-old children, and the supportive treatment is enough in most of them. The prevention of infection is possible with the knowledge of transmission routes and administration of effective vaccination programs.
Keywords
Acute hepatitis B Epidemiology Management PreventionReferences
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