Innate Immunity

  • Vladimir V. Klimov


The first line of defense is the innate immunity including phagocytosis, NETosis, natural cytotoxicity, pyroptosis, the formation of inflammasomes, etc. The reader can find the explanation of the pattern recognition theory, a novel concept in immunology. Clinical comments include the description of primary immunodeficiencies on the base of mutations in genes important for the innate immunity and the features of acute physiological, acute pathological, and chronic pathological inflammation.

Supplementary material

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Vladimir V. Klimov
    • 1
  1. 1.Clinical Immunology and Allergy DepartmentSiberian State Medical UniversityTomskRussia

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