Biological Mechanisms of Somatization

  • Kyung Bong Koh


Biological mechanisms of somatization include physiological activities, alterations in blood flow and endocrine system, physiological arousal induced by stress, pain threshold, gate control mechanism, brain imaging and electroencephalogram (EEG), abnormalities in cerebral hemispheres and hemispheric asymmetry, disturbances in wakefulness and concentration, serotonin, immunity, and genetic factors. Some of biological mechanisms may help differentiate between somatizing disorders and other mental disorders, such as depressive disorders and anxiety disorders. Further studies are needed to elucidate the brain-immune and genetic-immune interactions in these disorders.


Biological mechanisms Somatization Somatizing disorders Depressive disorders Anxiety disorders 


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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  • Kyung Bong Koh
    • 1
  1. 1.Department of PsychiatryYonsei University College of MedicineSeoulKorea

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