Merkel Cell Carcinoma

  • Iris K. Noh
  • Christopher K. BichakjianEmail author


Merkel cell carcinoma (MCC), also referred to as primary cutaneous neuroendocrine carcinoma , is a rare but potentially aggressive cutaneous malignancy. First described in 1972 as trabecular carcinoma, MCC is believed to arise from Merkel cells which function as mechanoreceptors in the skin (Tang and Toker, Cancer 42(5):2311–2321, 1978; Toker, Arch Dermatol 105(1):107–110, 1972).


Merkel cell carcinoma Merkel cell polyomavirus Immunotherapy Radiation therapy Sentinel lymph node biopsy 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of DermatologyMichigan MedicineAnn ArborUSA

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