Cancer Prevention

  • Mita Sanghavi GoelEmail author
  • Linda Overholser


Cancer prevention refers to activities that help to reduce the incidence and overall burden of cancer. It can include screening, but more broadly encompasses other activities in the clinical setting as well as individual behaviors. Traditionally, prevention has been defined in tiers of primary, secondary, and tertiary prevention.


  1. Ashton-Prolla P, Giacomazzi J, Schmidt AV, Roth FL, Palmero EI, Kalakun L, et al. Development and validation of a simple questionnaire for the identification of hereditary breast cancer in primary care. BMC Cancer. 2009;9:283.Google Scholar
  2. Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F, Bouvard V, et al. Carcinogenicity of alcoholic beverages. Lancet Oncol. 2007;8(4):292–3.CrossRefGoogle Scholar
  3. Evans DG, Eccles DM, Rahman N, Young K, Bulman M, Amir E, et al. A new scoring system for the chances of identifying a BRCA1/2 mutation outperforms existing models including BRCAPRO. J Med Genet. 2004;41(6):474–80.CrossRefGoogle Scholar
  4. Fletcher RH, Fletcher SW, Fletcher GS. Clinical epidemiology: the essentials. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2012.Google Scholar
  5. Gilpin CA, Carson N, Hunter AG. A preliminary validation of a family history assessment form to select women at risk for breast or ovarian cancer for referral to a genetics center. Clin Genet. 2000;58(4):299–308.CrossRefGoogle Scholar
  6. Hampel H, Bennett RL, Buchanan A, Pearlman R, Wiesner GL. A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment. Genet Med. 2014;17:70.CrossRefGoogle Scholar
  7. Hoskins KF, Zwaagstra A, Ranz M. Validation of a tool for identifying women at high risk for hereditary breast cancer in population-based screening. Cancer. 2006;107(8):1769–76.CrossRefGoogle Scholar
  8. IARC Helicobacter pylori Working Group. Helicobacter pylori eradication as a strategy for preventing gastric cancer. (IARC Working Group Reports, No. 8). Lyon, France: International Agency for Research on Cancer; 2014b2014a.
  9. Islami F, Goding Sauer A, Miller KD, Siegel RL, Fedewa SA, Jacobs EJ, et al. Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States. CA Cancer J Clin. 2018;68(1):31–54.CrossRefGoogle Scholar
  10. Kushi LH, Doyle C, McCullough M, Rock CL, Demark-Wahnefried W, Bandera EV, et al. American Cancer Society guidelines on nutrition and physical activity for cancer prevention: reducing the risk of cancer with healthy food choices and physical activity. CA Cancer J Clin. 2012;62(1):30–67.CrossRefGoogle Scholar
  11. Lim U, Subar AF, Mouw T, Hartge P, Morton LM, Stolzenberg-Solomon R, et al. Consumption of aspartame-containing beverages and incidence of hematopoietic and brain malignancies. Cancer Epidemiol Biomark Prev. 2006;15(9):1654–9.CrossRefGoogle Scholar
  12. Lum A, Le Marchand L. A simple mouthwash method for obtaining genomic DNA in molecular epidemiological studies. Cancer Epidemiol Biomark Prev. 1998;7(8):719–24.Google Scholar
  13. Moyer VA. Vitamin, mineral, and multivitamin supplements for the primary prevention of cardiovascular disease and cancer: U.S. Preventive services Task Force recommendation statement. Ann Intern Med. 2014a;160(8):558–64.CrossRefGoogle Scholar
  14. Moyer VA, on behalf of the USPSTF. Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. preventive services task force recommendation statement. Ann Intern Med. 2014b;160(4):271–81.CrossRefGoogle Scholar
  15. Nelson DE, Jarman DW, Rehm J, Greenfield TK, Rey G, Kerr WC, et al. Alcohol-attributable cancer deaths and years of potential life lost in the United States. Am J Pub Health. 2013;103(4):641–8.CrossRefGoogle Scholar
  16. NTP (National Toxicology Program). Report on carcinogens, fourteenth edition. Research Triangle Park: U.S. Department of Health and Human Services; 2016.Google Scholar
  17. Pilarski R, Burt R, Kohlman W, Pho L, Shannon KM, Swisher E. Cowden syndrome and the PTEN hamartoma tumor syndrome: systematic review and revised diagnostic criteria. J Natl Cancer Inst. 2013;105(21):1607–16.CrossRefGoogle Scholar
  18. Piñeiro B, Simmons VN, Palmer AM, Correa JB, Brandon TH. Smoking cessation interventions within the context of low-dose computed tomography lung cancer screening: a systematic review. Lung Cancer. 2016;98:91–8.CrossRefGoogle Scholar
  19. Whittemore AS, Gong G, John EM, McGuire V, Li FP, Ostrow KL, et al. Prevalence of BRCA1 mutation carriers among U.S. non-Hispanic whites. Cancer Epidemiol Biomark Prev. 2004;13(12):2078–83.Google Scholar

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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Division of General Internal Medicine and GeriatricsFeinberg School of Medicine, Northwestern UniversityChicagoUSA
  2. 2.Division of General Internal MedicineUniversity of Colorado School of MedicineAuroraUSA

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