The Role of Synovium and Synovial Fluid in Joint Hemostasis

  • Michael L. Redondo
  • David R. Christian
  • Adam B. YankeEmail author


All diarthrodial joints are lined by synovium, a specialized connective tissue. Synovium plays a significant role in maintaining the intra-articular environment. The function of normal synovium is to maintain homeostasis within the intra-articular environment through maintenance of the synovial surface, lubrication of the articular surface, and production of synovial fluid. The synovium and synovial fluid are altered in the setting of osteoarthritis and trauma. The purpose of this chapter is to describe the current literature on synovium and synovial fluid, the resulting biologic milieu in the joint, as well as their lasting effects on overall joint health.


Synovium Synovial fluid Cartilage restoration Biomarkers Joint homeostasis 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Michael L. Redondo
    • 1
  • David R. Christian
    • 1
  • Adam B. Yanke
    • 1
    Email author
  1. 1.Department of Orthopedic SurgeryRush University Medical CenterChicagoUSA

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