Simple Limbal Epithelial Transplantation: An Update

  • Nandini Venkateswaran
  • Guillermo AmescuaEmail author
Part of the Essentials in Ophthalmology book series (ESSENTIALS)


Limbal stem cell deficiency (LSCD) is a condition characterized by the delay or failure of normal corneal epithelialization. This aberrant process can lead to conjunctivalization, superficial corneal neovascularization, and ultimately poor healing of the corneal surface, resulting in corneal blindness. The treatment of LSCD can be complex and can range from conservative approaches to surgical interventions. Recently, simple limbal epithelial transplantation (SLET) has emerged as a novel surgical technique for the treatment of unilateral LSCD with promising results. In this chapter, we review the SLET surgical technique and discuss the advantages and drawbacks of this surgical modality.


Limbal stem cell deficiency Simple limbal epithelial transplantation 



We would like to thank Dr. Anat Galor MD MSPH for assistance in obtaining clinical photographs used in this publication.

Compliance with Ethical Requirements

Conflict of InterestNandini Venkateswaran and Guillermo Amescua declare that they have no conflict of interest.

Informed ConsentNo human studies were carried out by the authors for this article.

No animal studies were carried out by the authors for this article.


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Bascom Palmer Eye Institute, University of Miami, Department of OphthalmologyMiamiUSA

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