Clinical Management of One-Lung Ventilation

  • Travis Schisler
  • Jens LohserEmail author


One-lung ventilation (OLV) is a recognized and modifiable risk factor for acute lung injury. OLV needs to be individualized to the patient’s predicted body weight and their particular lung mechanics. Protective OLV is a combination of small, physiologic tidal volumes with consequently low ventilating pressures and routine, individualized PEEP to facilitate open lung ventilation. Ventilator-induced lung injury is preventable by minimizing driving pressure, which is a direct correlate of transpulmonary stress and strain. In patients at particular risk of lung injury, the use of permissive hypercapnia may facilitate a decrease in the mechanical strain onto the lung. Hypoxemia during one-lung ventilation is now rare and often secondary to alveolar de-recruitment in the face of hypoventilation. Management of hypoxemia requires a structured treatment algorithm.


One-lung ventilation Protective ventilation Acute lung injury Postoperative respiratory complications Driving pressure Thoracic surgery 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Anesthesiology, Pharmacology, and TherapeuticsUniversity of British Columbia, Vancouver General HospitalVancouverCanada

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