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Anesthesia for Patients with End-Stage Lung Disease

  • Florin Costescu
  • Martin MaEmail author
Chapter

Abstract

Preoperative optimization with pulmonary rehabilitation, smoking cessation, and education can improve surgical outcomes in patients with end-stage lung disease (ESLD). ESLD is associated with a high incidence of pulmonary hypertension and right ventricular dysfunction. The anesthetic goals for these patients include optimizing preload, maintaining a low normal heart rate, maintaining contractility, decreasing pulmonary vascular resistance, and ensuring systemic pressures that are greater than pulmonary pressures. Compared with general anesthesia, regional anesthesia and analgesia may reduce the risk of pulmonary complications and perioperative morbidity. Even mild pulmonary insults will be poorly tolerated by patients with ESLD. Ventilation strategies that utilize low tidal volumes and low airway pressures may reduce the risk of volutrauma, barotrauma, and acute lung injury. Intraoperative management can facilitate early recovery and early tracheal extubation after general anesthesia. Short-acting anesthetic agents are recommended. As elimination of inhalational agents is impaired by ESLD, total intravenous anesthesia (TIVA) may be preferred. Maintenance of normothermia will avoid increases in ventilatory demand associated with postoperative shivering. Effective postoperative analgesia is essential in patients with ESLD. Regional analgesia is preferred over parenteral opioid analgesics. Adjuvant pain medications which have an opioid-sparing effect should be used. Chronic obstructive pulmonary disease is a common cause of ESLD. Severe airflow obstruction results in a high risk of air trapping, pneumothorax, and dynamic hyperinflation. In addition to aggressive bronchodilation, ventilation with low inspiratory/expiratory ratios (1:3 to 1:4.5) and low respiratory rates (6–10/min) will optimize expiratory airflow. Cystic fibrosis is a multisystemic disease that results in abnormally viscous secretions. Inability to clear pulmonary secretions results in airflow obstruction and chronic infection. Management focuses on improving sputum clearance and minimizing airway obstruction. The interstitial lung diseases cause lung restriction and are characterized by chronic inflammation and fibrosis. Ventilation strategies that minimize tidal volume and airway pressures should be used.

Keywords

Preoperative evaluation Preoperative optimization Anesthesia Chronic obstructive lung disease Cystic fibrosis Interstitial lung diseases 

References

  1. 1.
    Bluman LG, Mosca L, Newman N, et al. Preoperative smoking habits and postoperative pulmonary complications. Chest. 1998;113:883–9.PubMedCrossRefGoogle Scholar
  2. 2.
    Kemp SV, Polkey MI, Shah PL. The epidemiology, etiology, clinical features, and natural history of emphysema. Thorac Surg Clin. 2009;19(2):149–58.PubMedCrossRefGoogle Scholar
  3. 3.
    Fischer SP, Bader AM, Sweitzer BJ. Preoperative evaluation. In: Miller RD, Eriksson LI, Fleisher LA, Wiener-Kronish JP, Young WL, editors. Miller’s anesthesia. 7th ed. Philadelphia: Churchill Livingstone; 2009. p. 1022.Google Scholar
  4. 4.
    Warner MA, Offord KP, Warner ME, et al. Role of preoperative cessation of smoking and other factors in postoperative pulmonary complications: a blinded prospective study of coronary artery bypass patients. Mayo Clin Proc. 1989;64(6):609–16.PubMedCrossRefGoogle Scholar
  5. 5.
    Nakagawa M, Tanaka H, Tsukuma H. Relationship between the duration of the preoperative smoke-free period and the incidence of postoperative pulmonary complications after pulmonary surgery. Chest. 2001;120:705–10.CrossRefGoogle Scholar
  6. 6.
    Wong J, Lam DP, Abrishami A, Chan MTV, Chung F. Short-term preoperative smoking cessation and postoperative complications: a systematic review and meta-analysis. Can J Anesth. 2012;59:268–79.PubMedCrossRefGoogle Scholar
  7. 7.
    Møller AM, Villebro N, Tom Pedersen T, Tønnesen H. Effect of preoperative smoking intervention on postoperative complications: a randomised clinical trial. Lancet. 2002;359:114–7.PubMedCrossRefGoogle Scholar
  8. 8.
    Thomsen T, Villebro N, Møller AM. Interventions for preoperative smoking cessation. Cochrane Database Syst Rev. 2014;3:CD002294.Google Scholar
  9. 9.
    Thomsen T, Tønnesen H, Møller AM. Effect of preoperative smoking cessation interventions on postoperative complications and smoking cessation. Brit J Surg. 2009;96:451–61.PubMedCrossRefGoogle Scholar
  10. 10.
    Lee SM, Landry J, Jones PM, Buhrmann O, Morley-Forster P. Long-term quit rates after a perioperative smoking cessation randomized controlled trial. Anesth Analg. 2015;120:582–7.PubMedCrossRefGoogle Scholar
  11. 11.
    ASA task force on smoking cessation. Statement on smoking cessation. 2008.Google Scholar
  12. 12.
    Wong J, Abrishami A, Yang Y, Zaki A, Friedman Z, Selby P, et al. A perioperative smoking cessation intervention with varenicline - a double-blind, randomized, placebo-controlled trial. Anesthesiology. 2012;117:755–64.PubMedCrossRefGoogle Scholar
  13. 13.
    Spruit MA, Singh SJ, Garvey C, ZuWallack R, Nici L, Rochester C, et al. ATS/ERS Task Force on Pulmonary Rehabilitation. An Official American Thoracic Society/European Respiratory Society Statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med 2013;188(8):e13–64.Google Scholar
  14. 14.
    Casaburi R, Patessio A, Ioli F, et al. Reductions in exercise lactic acidosis and ventilation as a result of exercise training in patients with obstructive lung disease. Am Rev Respir Dis. 1991;143(1):9–18.PubMedCrossRefGoogle Scholar
  15. 15.
    Meyer T, Faude O, Scharhag J, et al. Is lactic acidosis a cause of exercise induced hyperventilation at the respiratory compensation point? Br J Sports Med. 2004;38(5):622–5.PubMedPubMedCentralCrossRefGoogle Scholar
  16. 16.
    Kesten S. Pulmonary rehabilitation and surgery for end-stage lung disease. Clin Chest Med. 1997;18(2):173–81.PubMedCrossRefGoogle Scholar
  17. 17.
    Donahoe M. Nutritional support in advanced lung disease. The pulmonary cachexia syndrome. Clin Chest Med. 1997;18(3):547–61.PubMedCrossRefGoogle Scholar
  18. 18.
    Casaburi R, ZuWallack R. Pulmonary rehabilitation for management of chronic obstructive pulmonary disease. N Engl J Med. 2009;360(13):1329–35.PubMedCrossRefGoogle Scholar
  19. 19.
    Ries AL, Bauldoff GS, Carlin BW, et al. Pulmonary rehabilitation: joint ACCP/AACVPR evidence-based clinical practice guidelines. Chest. 2007;131(5 Suppl):4S–2.PubMedCrossRefGoogle Scholar
  20. 20.
    McCarthy B, Casey D, Devane D, Murphy K, Murphy E, Lacasse Y. Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2015;2:CD003793.Google Scholar
  21. 21.
    Dowman L, Hill CJ, Holland AE. Pulmonary rehabilitation for interstitial lung disease. Cochrane Database Syst Rev. 2014;10:CD006322.Google Scholar
  22. 22.
    Klijn PHC, Oudshoorn A, van der Ent CK, van der NET J, Kimpen JL, Helders PJM. Effects of anaerobic training in children with cystic fibrosis – a randomized controlled study. Chest. 2004;125:1299–305.PubMedCrossRefGoogle Scholar
  23. 23.
    Radtke T, Nolan SJ, Hebestreit H, Kriemler S. Physical exercise training for cystic fibrosis. Cochrane Database Syst Rev. 2015;6:CD002768.Google Scholar
  24. 24.
    Carson KV, Chandratilleke MG, Picot J, Brinn MP, Esterman AJ, Smith BJ. Physical training for asthma. Cochrane Database Syst Rev. 2013;9:CD001116.Google Scholar
  25. 25.
    Mendes FAR, Goncalves RC, Nunes MPT, Saraiva-Romanholo BM, Cukier A, Stelmach R, et al. Effects of aerobic training on psychosocial morbidity and symptoms in patients with asthma - a randomized clinical trial. Chest. 2010;138(2):331–3.PubMedCrossRefGoogle Scholar
  26. 26.
    Turner A, Eastwood P, Cook A, Jenkins S. Improvements in symptoms and quality of life following exercise training in older adults with moderate/severe persistent asthma. Respiration. 2011;81:302–10.PubMedCrossRefGoogle Scholar
  27. 27.
    Uchi M, Saji T, Harada T. Feasibility of cardiopulmonary rehabilitation in patients with idiopathic pulmonary arterial hypertension treated with intravenous prostacyclin infusion therapy. J Cardiol. 2005;46(5):183–93.PubMedGoogle Scholar
  28. 28.
    National Emphysema Treatment Trial Research Group. A randomized trial comparing lung-volume–reduction surgery with medical therapy for severe emphysema. N Engl J Med. 2003;348:2059–73.CrossRefGoogle Scholar
  29. 29.
    Cesario A, Ferri L, Galetta D, et al. Pre-operative pulmonary rehabilitation and surgery for lung cancer. Lung Cancer. 2007;57(1):118–9.PubMedPubMedCentralCrossRefGoogle Scholar
  30. 30.
    Bobbio A, Chetta A, Ampollini L, Primomo GL, Internullo E, Carbognani P, et al. Preoperative pulmonary rehabilitation in patients undergoing lung resection for non-small cell lung cancer. Eur J Cardiothorac Surg. 2008;33:95–8.PubMedCrossRefGoogle Scholar
  31. 31.
    Stefanelli F, Meoli I, Cobuccio R, Curcio C, Amore D, Casazza D, et al. High-intensity training and cardiopulmonary exercise testing in patients with chronic obstructive pulmonary disease and non-small-cell lung cancer undergoing lobectomy. Eur J Cardiothorac Surg. 2013;44:e260–5.PubMedCrossRefGoogle Scholar
  32. 32.
    Rajendran AJ, Pandurangi UM, Murali R, et al. Pre-operative short term pulmonary rehabilitation for patients of chronic obstructive pulmonary disease undergoing coronary artery bypass graft surgery. Indian Heart J. 1998;50(5):531–4.PubMedGoogle Scholar
  33. 33.
    Simonneau G, Gatzoulis MA, Adatia I, Celermajer D, Denton C, Ghofrani A, et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol. 2013;62:D34–41.PubMedCrossRefGoogle Scholar
  34. 34.
    Lawrence VA, Cornell JE, Smetana GW. Strategies to reduce postoperative pulmonary complication after noncardiothoracic surgery: systemic review for the American College of Physicians. Ann Intern Med. 2006;144:596–608.PubMedCrossRefGoogle Scholar
  35. 35.
    Olsen MF, Hahn I, Nordgren S, et al. Randomized controlled trial of prophylactic chest physiotherapy in major abdominal surgery. Br J Surg. 1997;84:1535–8.CrossRefGoogle Scholar
  36. 36.
    Hulzebos EH, Helders PJ, Favié NJ, et al. Preoperative intensive inspiratory muscle training to prevent postoperative pulmonary complications in high-risk patients undergoing CABG surgery: a randomized clinical trial. JAMA. 2006;296(15):1851–7.PubMedCrossRefGoogle Scholar
  37. 37.
    Katsura M, Kuriyama A, Takeshima T, Fukuhara S, Furukawa TA. Preoperative inspiratory muscle training for postoperative pulmonary complications in adults undergoing cardiac and major abdominal surgery. Cochrane Database Syst Rev. 2015;10:CD010356.Google Scholar
  38. 38.
    Warner DO. Preventing postoperative pulmonary complications. Anesthesiology. 2000;92:1467–72.PubMedPubMedCentralCrossRefGoogle Scholar
  39. 39.
    Bossone E, Ferrara F, Grunig E. Echocardiography in pulmonary hypertension. Curr Opin Cardiol. 2015;30:574–86.PubMedCrossRefGoogle Scholar
  40. 40.
    Gay PC. Chronic obstructive pulmonary disease and sleep. Respir Care. 2004;49:39–51.PubMedGoogle Scholar
  41. 41.
    Bhullar S, Phillips B. Sleep in COPD patients. COPD. 2005;2:355–61.PubMedCrossRefGoogle Scholar
  42. 42.
    Rafanan AL, Golish JA, Dinner DS, et al. Nocturnal hypoxemia is common in primary pulmonary hypertension. Chest. 2001;120:894–9.PubMedCrossRefGoogle Scholar
  43. 43.
    Agarwal S, Richardson B, Krishnan V, et al. Interstitial lung disease and sleep: what is known? Sleep Med. 2009;10:947–51.PubMedCrossRefGoogle Scholar
  44. 44.
    Milross MA, Piper AJ, Dobbin CJ, et al. Sleep disordered breathing in cystic fibrosis. Sleep Med Rev. 2004;8:295–308.PubMedCrossRefGoogle Scholar
  45. 45.
    Schneider H. Sleep-related breathing disorders in COPD. In: Stoller JK, Badr MS, Hollingsworth H, Eichler AF, editors. UpToDate. Waltham: UpToDate; 2017.Google Scholar
  46. 46.
    Fischer LG, Van Aken H, Bürkle H. Management of pulmonary hypertension: physiological and pharmacological considerations for anesthesiologists. Anesth Analg. 2003;96(6):1603–16.PubMedCrossRefGoogle Scholar
  47. 47.
    Blaise G, Langleben D, Hubert B. Pulmonary arterial hypertension: pathophysiology and anesthetic approach. Anesthesiology. 2003;99(6):1415–32.PubMedCrossRefPubMedCentralGoogle Scholar
  48. 48.
    Rovedder PM, Ziegler B, Pinotti AF, et al. Prevalence of pulmonary hypertension evaluated by Doppler echocardiography in a population of adolescent and adult patients with cystic fibrosis. J Bras Pneumol. 2008;34(2):83–90.PubMedCrossRefGoogle Scholar
  49. 49.
    Han MK, McLaughlin VV, Criner GJ, et al. Pulmonary diseases and the heart. Circulation. 2007;116(25):2992–3005.PubMedCrossRefGoogle Scholar
  50. 50.
    Andersen KH, Iversen M, Kjaergaard J, Mortensen J, Nielsen-Kudsk JE, Bendstrup E, et al. Prevalence, predictors, and survival in pulmonary hypertension related to end-stage chronic obstructive pulmonary disease. J Heart Lung Transplant. 2012;31:373–80.PubMedCrossRefGoogle Scholar
  51. 51.
    Subramaniam K, Yared JP. Management of pulmonary hypertension in the operating room. Semin Cardiothorac Vasc Anesth. 2007;11:119–36.PubMedCrossRefGoogle Scholar
  52. 52.
    Stoelting RK, Hillier SC. Nonbarbituate intravenous anesthetic drugs. In: Stoelting RK, Hillier SC, editors. Pharmacology and physiology in anesthesia practice. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2006. p. 155–79.Google Scholar
  53. 53.
    Fox C, Kalarickal PL, Yarborough MJ, et al. Perioperative management including new pharmacological vistas for patients with pulmonary hypertension for noncardiac surgery. Curr Opin Anaesthesiol. 2008;21:467–72.PubMedCrossRefGoogle Scholar
  54. 54.
    Friesen RH, Williams GD. Anesthetic management of children with pulmonary arterial hypertension. Paediatr Anaesth. 2008;18:208–16.PubMedCrossRefPubMedCentralGoogle Scholar
  55. 55.
    Friesen RH, Twite MD, Nichols CS, Cardwell KA, Pan Z, Darst JR, et al. Hemodynamic response to ketamine in children with pulmonary hypertension. Paediatr Anaesth. 2016;26:102–8.PubMedPubMedCentralCrossRefGoogle Scholar
  56. 56.
    Tayama E, Ueda T, Shojima T, et al. Arginine vasopressin is an ideal drug after cardiac surgery for the management of low systemic vascular resistant hypotension concomitant with pulmonary hypertension. Interact Cardiovasc Thorac Surg. 2007;6:715–9.PubMedPubMedCentralCrossRefGoogle Scholar
  57. 57.
    Price LC, Forrest P, Sodhi V, et al. Use of vasopressin after Caesarean section in idiopathic pulmonary arterial hypertension. Br J Anaesth. 2007;99:552–5.PubMedPubMedCentralCrossRefGoogle Scholar
  58. 58.
    Smith AM, Elliot CM, Kiely DG, et al. The role of vasopressin in cardiorespiratory arrest and pulmonary hypertension. QJM. 2006;99:127–33.PubMedCrossRefGoogle Scholar
  59. 59.
    Currigan DA, Hughes RJA, Wright CE, Angus JA, Soeding PF. Vasoconstrictor responses to vasopressor agents in human pulmonary and radial arteries an in vitro study. Anesthesiology. 2014;121:930–6.PubMedPubMedCentralCrossRefGoogle Scholar
  60. 60.
    Hajjar LA, Vincent JL, Galas FRBG, Rhodes A, Landoni G, Osawa EA, et al. Vasopressin versus norepinephrine in patients with vasoplegic shock after cardiac surgery the VANCS randomized controlled trial. Anesthesiology. 2017;126:85–93.PubMedCrossRefGoogle Scholar
  61. 61.
    Sandham JD, Hull RD, Brant RF, et al. A randomized, controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients. N Engl J Med. 2003;348:5–14.PubMedCrossRefGoogle Scholar
  62. 62.
    Rodgers A, Walker N, Schug S, et al. Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials. BMJ. 2000;321:1493.PubMedPubMedCentralCrossRefGoogle Scholar
  63. 63.
    Park WY, Thompson JS, Lee KK. Effect of epidural anesthesia and analgesia on perioperative outcome: a randomized, controlled Veterans Affairs cooperative study. Ann Surg. 2001;234:560–9.PubMedCrossRefGoogle Scholar
  64. 64.
    Rigg JR, Jamrozik K, Myles PS, et al. Epidural anaesthesia and analgesia and outcome of major surgery: a randomised trial. Lancet. 2002;359:1276–82.PubMedPubMedCentralCrossRefGoogle Scholar
  65. 65.
    Tziavrangos E, Schug SA. Regional anaesthesia and perioperative outcome. Curr Opin Anaesthesiol. 2006;19:521–5.PubMedCrossRefGoogle Scholar
  66. 66.
    Gulur P, Nishimori M, Ballantyne JC. Regional anaesthesia versus general anaesthesia, morbidity and mortality. Best Pract Res Clin Anaesthesiol. 2006;20:249–63.PubMedCrossRefGoogle Scholar
  67. 67.
    Breen P, Park KW. General anesthesia versus regional anesthesia. Int Anesthesiol Clin. 2002;40:61–71.PubMedCrossRefGoogle Scholar
  68. 68.
    Hausman MS Jr, Jewell ES, Engoren M. Regional versus general anesthesia in surgical patients with chronic obstructive pulmonary disease: does avoiding general anesthesia reduce the risk of postoperative complications? Anesth Analg. 2015;120:1405–12.PubMedCrossRefGoogle Scholar
  69. 69.
    Popping DM, Elia N, Van Aken HK, Marret E, Schug SA, Kranke P, et al. Impact of epidural analgesia on mortality and morbidity after surgery - systematic review and meta-analysis of randomized controlled trials. Ann Surg. 2014;259:1056–67.PubMedCrossRefGoogle Scholar
  70. 70.
    Rock P, Rich PB. Postoperative pulmonary complications. Curr Opin Anaesthesiol. 2003;16:123–31.PubMedCrossRefGoogle Scholar
  71. 71.
    Kozian A, Schilling T, Hachenberg T. Non-analgetic effects of thoracic epidural anaesthesia. Curr Opin Anaesthesiol. 2005;18:29–34.PubMedCrossRefGoogle Scholar
  72. 72.
    Drummond GB. Diaphragmatic dysfunction: an outmoded concept. Br J Anaesth. 1998;80:277–80.PubMedCrossRefGoogle Scholar
  73. 73.
    Savas JF, Litwack R, Davis K, et al. Regional anesthesia as an alternative to general anesthesia for abdominal surgery in patients with severe pulmonary impairment. Am J Surg. 2004;188(5):603–5.PubMedCrossRefGoogle Scholar
  74. 74.
    van Zundert AA, Stultiens G, Jakimowicz JJ, et al. Segmental spinal anaesthesia for cholecystectomy in a patient with severe lung disease. Br J Anaesth. 2006;96:464–6.PubMedCrossRefGoogle Scholar
  75. 75.
    Kalko Y, Ugurlucan M, Basaran M, et al. Epidural anaesthesia and mini-laparotomy for the treatment of abdominal aortic aneurysms in patients with severe chronic obstructive pulmonary disease. Acta Chir Belg. 2007;107(3):307–12.PubMedCrossRefGoogle Scholar
  76. 76.
    Tarhan S, Moffitt EA, Sessler AD, Douglas WW, Taylor WF. Risk of anesthesia and surgery in patients with chronic bronchitis and chronic obstructive pulmonary disease. Surgery. 1973;74:720–6.PubMedGoogle Scholar
  77. 77.
    van Lier F, van der Geest PJ, Hoeks SE, van Gestel YRBM, Hol JW, Sin DD, et al. Epidural analgesia is associated with improved health outcomes of surgical patients with chronic obstructive pulmonary disease. Anesthesiology. 2011;115:315–21.PubMedCrossRefGoogle Scholar
  78. 78.
    Amato MB, Barbas CS, Medeiros DM, et al. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med. 1998;338:347.PubMedPubMedCentralCrossRefGoogle Scholar
  79. 79.
    Futier E, Constantin JM, Paugam-Burtz C, Pascal J, Eurin M, Neuschwander A, IMPROVE Study Group. A trial of intraoperative low-tidal-volume ventilation in abdominal surgery. N Engl J Med. 2013;369:428–37.PubMedCrossRefGoogle Scholar
  80. 80.
    Amato MBP, Meade MO, Slutsky AS, Brochard L, Costa ELV, Schoenfeld DA, et al. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med. 2015;372:747–55.PubMedPubMedCentralCrossRefGoogle Scholar
  81. 81.
    Neto AS, Hemmes SNT, Barbas CSV, Beiderlinden M, Fernandez-Bustamante A, Futier E, et al. Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data. Lancet Respir Med. 2016;4:272–8034.PubMedPubMedCentralCrossRefGoogle Scholar
  82. 82.
    Lawrence VA, Cornell JE, Smetana GW, et al. Strategies to reduce postoperative pulmonary complications after noncardiothoracic surgery: systematic review for the American College of Physicians. Ann Intern Med. 2006;144:596–608.PubMedCrossRefGoogle Scholar
  83. 83.
    Abraham NS, Young JM, Solomon MJ. Meta-analysis of short-term outcomes after laparoscopic resection for colorectal cancer. Br J Surg. 2004;91:1111–24.PubMedCrossRefGoogle Scholar
  84. 84.
    Avidan MS, Maybrier HR, Abdallah AB, Jacobsohn E, Vlisides PE, Pryor KO, et al. PODCAST Research Group. Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial. Lancet 2017;390:267–75.Google Scholar
  85. 85.
    Conacher ID, Slinger PD. Pain management. In: Kaplan JA, Slinger PD, editors. Thoracic anesthesia. 3rd ed. Philadelphia: Churchill Livingstone; 2003. p. 436–62.Google Scholar
  86. 86.
    Groeben H. Epidural anesthesia and pulmonary function. J Anesth. 2006;20:290–9.PubMedCrossRefGoogle Scholar
  87. 87.
    Nelson R, Edwards S, Tse B. Prophylactic nasogastric decompression after abdominal surgery. Cochrane Database Syst Rev 2007;3:CD004929.Google Scholar
  88. 88.
    Global initiative for chronic obstructive lung disease – global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease – 2017 Report. www.goldcopd.org. Accessed on 26 March 2017.
  89. 89.
    Celli BR, Cote CG, Marin JM, et al. The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. N Engl J Med. 2004;350:1005–12.PubMedCrossRefGoogle Scholar
  90. 90.
    Salvi SS, Barnes PJ. Chronic obstructive pulmonary disease in non-smokers. Lancet. 2009;374:733–43.PubMedCrossRefGoogle Scholar
  91. 91.
    Spurzem JR, Rennard SI. Pathogenesis of COPD. Semin Respir Crit Care Med. 2005;26:142–53.PubMedCrossRefGoogle Scholar
  92. 92.
    Stroller J. Clinical manifestations, diagnosis, and natural history of alpha-1 antitrypsin deficiency. In: Barnes PJ, Hollingsworth H, editors. UpToDate. Waltham: UpToDate; 2017.Google Scholar
  93. 93.
    McGeachie MJ, Yates KP, Zhou X, Guo F, Sternberg AL, Van Natta ML, et al. CAMP Research Group. Patterns of growth and decline in lung function in persistent childhood asthma. N Engl J Med. 2016;374:1842–52.PubMedCrossRefGoogle Scholar
  94. 94.
    West JB. Mechanics of breathing. In: West JB, editor. Respiratory physiology. 5th ed. Baltimore: Williams & Wilkins; 1990. p. 117–32.Google Scholar
  95. 95.
    Pepin V, Saey D, Laviolette L, Maltais F. Exercise capacity in chronic obstructive pulmonary disease: mechanisms of limitation. COPD. 2007;4:195–204.PubMedCrossRefGoogle Scholar
  96. 96.
    O’Donnell DE, Parker CM. COPD exacerbations-3: pathophysiology. Thorax. 2006;61:354–61.PubMedPubMedCentralCrossRefGoogle Scholar
  97. 97.
    Ben-David B, Stonebreaker VC, Hershman R. Survival after failed intraoperative resuscitation: a case of “Lazarus syndrome”. Anesth Analg. 2001;92:690–2.PubMedCrossRefGoogle Scholar
  98. 98.
    Edrich T, Sadovnikoff N. Anesthesia for patients with severe chronic obstructive pulmonary disease. Curr Opin Anaesthesiol. 2010;23:18–24.PubMedCrossRefGoogle Scholar
  99. 99.
    West JB. Control of ventilation. In: West JB, editor. Respiratory physiology. 5th ed. Baltimore: Williams & Wilkins; 1990. p. 117–32.Google Scholar
  100. 100.
    Hirshman CA, McCullough RE, Weil JV. Normal values for hypoxic and hypercapnic ventilatory drives in man. J Appl Physiol. 1975;38:1095–8.PubMedCrossRefGoogle Scholar
  101. 101.
    Feller-Kopman DJ, Schwartzstein RM. In: Stoller JK, editor. Mechanisms, causes and effects of hypercapnia. Waltham: UpToDate; 2017.Google Scholar
  102. 102.
    Aubier M, Murciano D, Fournier M, et al. Central respiratory drive in acute respiratory failure of patients with chronic obstructive pulmonary disease. Am Rev Respir Dis. 1980;122:191–9.PubMedCrossRefGoogle Scholar
  103. 103.
    Aubier M, Murciano D, Milic-Emili J, et al. Effects of the administration of O2 on ventilation and blood gases in patients with chronic obstructive pulmonary disease during acute respiratory failure. Am Rev Respir Dis. 1980;122:747–54.PubMedCrossRefGoogle Scholar
  104. 104.
    Morgan MD, Edwards CW, Morris J, et al. Origin and behaviour of emphysematous bullae. Thorax. 1989;44:533–8.PubMedPubMedCentralCrossRefGoogle Scholar
  105. 105.
    Caramez MP, Borges JB, Tucci MR, et al. Paradoxical responses to positive end-expiratory pressure in patients with airway obstruction during controlled ventilation. Crit Care Med. 2005;33:1519–28.PubMedPubMedCentralCrossRefGoogle Scholar
  106. 106.
    Jolliet P, Watremez C, Roeseler J, et al. Comparative effects of helium-oxygen and external positive end-expiratory pressure on respiratory mechanics, gas exchange, and ventilation-perfusion relationships in mechanically ventilated patients with chronic obstructive pulmonary disease. Intensive Care Med. 2003;29:1442–50.PubMedCrossRefGoogle Scholar
  107. 107.
    Karlet MC. An update on cystic fibrosis and implications for anesthesia. AANA J. 2000;68:141–8.PubMedGoogle Scholar
  108. 108.
    Howell PR, Kent N, Douglas MJ. Anaesthesia for the parturient with cystic fibrosis. Int J Obstet Anesth. 1993;2:152–8.PubMedCrossRefGoogle Scholar
  109. 109.
    Walsh TS, Young CH. Anaesthesia and cystic fibrosis. Anaesthesia. 1995;50:614–22.PubMedCrossRefGoogle Scholar
  110. 110.
    Cystic Fibrosis Foundation Patient Registry Annual Data Report 2015.Google Scholar
  111. 111.
    Stenbit A, Flume PA. Pulmonary complications in adult patients with cystic fibrosis. Am J Med Sci. 2008;335:55–9.PubMedCrossRefGoogle Scholar
  112. 112.
    McDougall RJ, Sherrington CA. Fatal pulmonary haemorrhage during anaesthesia for bronchial artery embolization in cystic fibrosis. Paediatr Anaesth. 1999;9:345–8.PubMedCrossRefGoogle Scholar
  113. 113.
    Simon RH. Cystic fibrosis: overview of the treatment of lung disease. In: Mallory GB, Hopin AG, editors. UpToDate. Waltham, MA: UpToDate; 2017.Google Scholar
  114. 114.
    Fuchs HJ, Borowitz DS, Christiansen DH, et al. Effect of aerosolized recombinant human DNase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis. The Pulmozyme Study Group. N Engl J Med. 1994;331:637–42.PubMedCrossRefGoogle Scholar
  115. 115.
    Elkins MR, Robinson M, Rose BR, et al. A controlled trial of long-term inhaled hypertonic saline in patients with cystic fibrosis. N Engl J Med. 2006;354:229–40.PubMedCrossRefGoogle Scholar
  116. 116.
    Ramsey BW, Davies J, McElvaney NG, Tullis E, Bell SC, Drevinek P, et al. A CFTR potentiator in patients with cystic fibrosis and the G551D mutation. N Engl J Med. 2011;365:1663–72.PubMedPubMedCentralCrossRefGoogle Scholar
  117. 117.
    Wainwright CE, Elborn JS, Ramsey BW, Marigowda G, Huang X, Cipolli M, et al. Lumacaftor–Ivacaftor in patients with cystic fibrosis homozygous for Phe508del CFTR. N Engl J Med. 2015;373:220–31.PubMedPubMedCentralCrossRefGoogle Scholar
  118. 118.
    Sabharwal S, Borowitz D. Cystic fibrosis: overview of gastrointestinal disease. In: Mallory GB, Heyman MB, Hoppin AG, editors. UpToDate. Waltham: UpToDate; 2017.Google Scholar
  119. 119.
    Tonelli MR, Aitken ML. Pregnancy in cystic fibrosis. Curr Opin Pulm Med. 2007;13:537–40.PubMedCrossRefGoogle Scholar
  120. 120.
    Patel EM, Swamy GK, Heine RP, Kuller JA, James AH, Grotegut CA. Medical and obstetric complications among pregnant women with cystic fibrosis. Am J Obstet Gynecol. 2015;212:98.e1–9.CrossRefGoogle Scholar
  121. 121.
    King Jr TE, Bradford WZ, Castro-Bernardini S, Fagan EA, Glaspole I, Glassberg MK, et al. ASCEND Study Group. A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis. N Engl J Med. 2014;370:2083–92.Google Scholar
  122. 122.
    Richeldi L, du Bois RM, Raghu G, Azuma A, Brown KK, Costabel U, et al. INPULSIS trial investigators. Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis. N Engl J Med. 2014;370:2071–82.Google Scholar
  123. 123.
    Carron M, Marchet A, Ori C. Supreme laryngeal mask airway for laparoscopic cholecystectomy in patient with severe pulmonary fibrosis. Br J Anaesth. 2009;103:778–9.PubMedCrossRefGoogle Scholar
  124. 124.
    Schure AY, Holzman RS. Anesthesia in a child with severe restrictive pulmonary dysfunction caused by chronic graft-versus-host disease. J Clin Anesth. 2000;12:482–6.PubMedCrossRefGoogle Scholar
  125. 125.
    Kayatta MO, Ahmed S, Hammel JA, Fernandez F, Pickens A, Miller D, et al. Surgical biopsy of suspected interstitial lung disease is superior to radiographic diagnosis. Ann Thorac Surg. 2013;96:399–401.PubMedCrossRefGoogle Scholar
  126. 126.
    Hutchinson JP, Fogarty AW, McKeever TM, Hubbard RB. In-hospital mortality after surgical lung biopsy for interstitial lung disease in the United States - 2000 to 2011. Am J Respir Crit Care Med. 2016;193:1161–7.PubMedCrossRefGoogle Scholar
  127. 127.
    Kumar P, Goldstraw P, Yamada K, Nicholson AG, Wells AU, Hansell DM, et al. Pulmonary fibrosis and lung cancer: risk and benefit analysis of pulmonary resection. J Thorac Cardiovasc Surg. 2003;125:1321–7.PubMedPubMedCentralCrossRefGoogle Scholar
  128. 128.
    Sato T, Teramukai S, Kondo H, Watanabe A, Ebina M, Kishi K, et al. Japanese Association for Chest Surgery. Impact and predictors of acute exacerbation of interstitial lung diseases after pulmonary resection for lung cancer. J Thorac Cardiovasc Surg. 2014;147:1604–11.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of AnesthesiaMcGill University Health Centre – Montreal General HospitalMontrealCanada
  2. 2.Department of Anesthesia and Pain ManagementUniversity Health Network, Toronto General HospitalTorontoCanada

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