Bone and Central Nervous System

  • Reiner Bartl
  • Christoph Bartl


Studies in the past decade have demonstrated evidence on the control of bone remodelling and metabolism by the central nervous system (CNS), by neurotransmitters released by bone cells and their stroma and by release of leptin. As shown by semithin sections and immunohistology of bone biopsies, the skeleton is densely innervated by autonomic and sensory nerve fibres.


Bone mass Anorexia nervosa Bone remodelling Eating disorder Sensory nerve fibre 

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Reiner Bartl
    • 1
  • Christoph Bartl
    • 1
    • 2
  1. 1.Osteoporosis and Bone CenterMunichGermany
  2. 2.Center of Orthopaedics and Sports MedicineMunichGermany

Personalised recommendations