Bone and Fatty Tissue

  • Reiner Bartl
  • Christoph Bartl


The number of overweight or obese people in the USA (69%) has reached epidemic proportions. Obesity is a national health problem there and in the meantime also recognised as a problem in Europe. Although obesity correlates with a higher bone mass and bone density, studies have shown that the bone quality in adults and children is inferior and in certain regions of the skeleton higher fracture rates have been observed. Osteoblasts and fat cells (adipocytes) derive from a common mesenchymal stem cells (MSC). Factors that increase adipogenesis typically inhibit the differentiation of osteoblastic cells.


Bone mass Mesenchymal stem cell Fracture risk Bone quality Lower bone mass 

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Reiner Bartl
    • 1
  • Christoph Bartl
    • 1
    • 2
  1. 1.Osteoporosis and Bone CenterMunichGermany
  2. 2.Center of Orthopaedics and Sports MedicineMunichGermany

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