Myelofibrosis/Osteomyelosclerosis Syndrome (MF/OMS)

  • Reiner Bartl
  • Christoph Bartl


The normal bone marrow has few fibres, and these are found mainly in association with trabecular bone surfaces and blood vessels. Fibrosis of the bone marrow takes place in response to many different toxic, inflammatory, osteolytic and malignant processes and is always of collagen type III. The basic disorders associated with bone marrow fibrosis are:


Collagen type Chronic myeloid leukaemia Myeloproliferative disorder Normal bone marrow Malignant process 

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Reiner Bartl
    • 1
  • Christoph Bartl
    • 1
    • 2
  1. 1.Osteoporosis and Bone CenterMunichGermany
  2. 2.Center of Orthopaedics and Sports MedicineMunichGermany

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