Epilepsia Partialis Continua

  • Roongroj Bhidayasiri
  • Daniel Tarsy
Part of the Current Clinical Neurology book series (CCNEU)


Epilepsia partialis continua (EPC) is a rare form of focal status epilepticus characterized by continuous regular or irregular clonic muscular twitching affecting a limited part of the body, sometimes aggravated by action or sensory stimuli, and occurring for a minimum of 1 h. Neurophysiologically, the diagnosis of EPC requires the demonstration of epileptiform EEG abnormalities, ideally with a fixed temporal association with the muscle jerks. Other abnormalities may include giant somatosensory-evoked potentials which demonstrate the cortical origin of the muscle jerks. EPC has been linked with both motor cortex and adjacent subcortical discharges. EPC may be due to vascular lesions (14%), inflammatory disorders (32%), head trauma (16%), neoplastic disorders (19%), and unknown causes (16%).


Motor Cortex Status Epilepticus Head Trauma Sensory Stimulus Rare Form 
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Supplementary material

The patient exhibits a train of regular jerks involving the right upper limb which are more prominent in the arm and elbow (Video contribution from Dr. Helen Ling, Chiang Mai University, Thailand).

Epilepsia partialis continua.mp4 (MP4 5,218KB)


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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Roongroj Bhidayasiri
    • 1
    • 2
  • Daniel Tarsy
    • 3
  1. 1.Chulalongkorn Center of Excellence on Parkinson’s Disease and Related DisordersChulalongkorn University HospitalBangkokThailand
  2. 2.Department of NeurologyDavid Geffen School of Medicine at UCLALos AngelesUSA
  3. 3.Department of NeurologyHarvard Medical School Beth Israel Deaconess Medical CenterBostonUSA

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