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Tremor-Dominant Parkinson’s Disease

  • Roongroj Bhidayasiri
  • Daniel Tarsy
Chapter
Part of the Current Clinical Neurology book series (CCNEU)

Abstract

Tremor-dominant Parkinson’s disease (PD) refers to patients who present initially with tremor with relatively mild bradykinesia and rigidity and who progress slowly over many years with tremor remaining the most prominent clinical symptom together with relatively mild bradykinesia, rigidity, and absence of postural instability. Several reports have subtyped patients with PD in order to compare their projected course over time. In PD, the disease process continues throughout life in a nonlinear fashion without spontaneous or treatment-induced remission. Although different subtyping schemes have been proposed, the most well-defined groups to emerge have been the tremor dominant, akinetic-rigid, and postural instability-gait disturbance (PIGD) subtypes.

Keywords

Disease Process Disease Rate Initial Visit Postural Instability Motor Complication 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Supplementary material

Tremor Dominant PD.mp4 (MP4 17,020KB)

The patient exhibits a large amplitude left hand resting tremor with re-emergent tremor of the left arm after several seconds when her arms are elevated. Facial expression is normal.

References

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  2. 2.Rajput AH, Sitte H, Rajput A, et al. Globus pallidus dopamine and Parkinson motor subtypes: clinical and brain biochemical correlation. Neurology. 2008;70:1403–10.PubMedCrossRefGoogle Scholar
  3. 3.Rajput AH, Voll A, Rajput ML, et al. Course in Parkinson disease subtypes. A 39-year clinicopathologic study. Neurology. 2009;73:206–12.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Roongroj Bhidayasiri
    • 1
    • 2
  • Daniel Tarsy
    • 3
  1. 1.Chulalongkorn Center of Excellence on Parkinson’s Disease and Related DisordersChulalongkorn University HospitalBangkokThailand
  2. 2.Department of NeurologyDavid Geffen School of Medicine at UCLALos AngelesUSA
  3. 3.Department of NeurologyHarvard Medical School Beth Israel Deaconess Medical CenterBostonUSA

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