Parvovirus B19

  • Morgan HakkiEmail author
  • Lynne Strasfeld


Parvovirus B19 was discovered in 1975, and the first reports associating B19 with human disease came 6 years later, when B19 was linked to cases of aplastic crisis in patients with sickle cell disease. Since then, B19 infection has become a recognized infectious complication in the immunocompromised host, including persons infected with human immunodeficiency virus (HIV), as well as solid organ (SOT) and hematopoietic cell transplant (HCT) recipients. While typically a benign, self-limited infection in immunocompetent hosts, B19 can have serious sequelae in the immunocompromised host. Fundamentals of disease pathogenesis, clinical manifestations, diagnosis, and treatment options are discussed.


Parvovirus B19, Solid organ transplant, Hematopoietic cell transplant, Virus 


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© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Oregon Health and Science University, Division of Infectious DiseasesPortlandUSA

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