Fibrous, Fibrohistiocytic, and Myofibroblastic Tumors of Intermediate Malignancy

  • Reena Singh
  • Aaron M. Udager
  • Steven D. Billings
  • Rajiv M. PatelEmail author


Fibrous, fibrohistiocytic, and myofibroblastic tumors of intermediate malignancy comprise a group of lesions that has a relatively high risk of local recurrence, but a limited risk of metastasis. Most of these tumors present in young adults as superficial masses. Members of this group include dermatofibrosarcoma protuberans and its numerous variants, plexiform fibrohistiocytic tumor, angiomatoid fibrous histiocytoma, giant cell tumor of soft tissue, and inflammatory myofibroblastic tumor.


Dermatofibrosarcoma protuberans Giant cell fibroblastoma Plexiform fibrohistiocytic tumor Angiomatoid fibrous histiocytoma Giant cell tumor of soft tissue Inflammatory myofibroblastic tumor 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Reena Singh
    • 1
  • Aaron M. Udager
    • 2
  • Steven D. Billings
    • 3
  • Rajiv M. Patel
    • 2
    Email author
  1. 1.Department of PathologyOregon Health and Science University School of MedicinePortlandUSA
  2. 2.Department of PathologyUniversity of Michigan Medical SchoolAnn ArborUSA
  3. 3.Department of PathologyCleveland ClinicClevelandUSA

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