Dialytic Therapy of Acute Kidney Injury

  • Alian A. Al-balas
  • Keith M. Wille
  • Ashita J. Tolwani


The management of patients with severe acute kidney injury (AKI) is largely supportive and includes renal replacement therapy (RRT). Available RRT modalities are intermittent hemodialysis (IHD); continuous renal replacement therapy (CRRT); hybrid therapies, known as prolonged intermittent renal replacement therapy (PIRRT); and peritoneal dialysis (PD). This chapter briefly reviews these dialytic options and the current evidence regarding the timing of RRT initiation, modality selection, and the practical considerations of the RRT prescription for AKI.


Acute kidney Injury (AKI) Renal replacement therapy (RRT) Continuous renal replacement therapy (CRRT) Hemodialysis Prolonged intermittent renal replacement therapy (PIRRT) Hemofiltration Sustained low-efficiency dialysis (SLED) 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Alian A. Al-balas
    • 1
  • Keith M. Wille
    • 2
  • Ashita J. Tolwani
    • 1
  1. 1.Division of NephrologyUniversity of Alabama at BirminghamBirminghamUSA
  2. 2.Division of Pulmonary, Allergy, and Critical Care MedicineUniversity of Alabama at BirminghamBirminghamUSA

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