Alzheimer’s Disease

  • Joseph T. Coyle
Part of the Readings from the Encyclopedia of Neuroscience book series (REN)


Alzheimer’s disease (AD) and senile dementia of the Alzheimer’s type, a distinction based primarily on age of onset, appear to be a similar, if not the same, disease process. It is now apparent that AD accounts for 40% to 60% of all cases of dementia with onset in adulthood and is two to threefold more frequent than multi-infarct dementia. It is estimated that 3–5% of individuals over the age of 65 suffer from AD, and current costs for nursing home care in the United States for patients afflicted with AD exceed $10 billion per year.

Further reading

  1. Katzman R, Terry RD, Bick KL, eds (1978): Alzheimer’s Disease: Senile Dementia and Related Disorders. New York: Raven PressGoogle Scholar
  2. Coyle JT, Price DL, DeLong MR (1983): Alzheimer’s disease: A disorder of cortical cholinergic innervation. Science 219: 1184–1190CrossRefGoogle Scholar
  3. Katzman RD, ed (1983): Biological Aspects of Alzheimer’s Disease. Cold Spring Harbor LaboratoryGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • Joseph T. Coyle

There are no affiliations available

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