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Surfactant System in Lung Injury

  • Patricia L. Haslam
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Abstract

The search for therapeutic agents to improve the clinical outcome in adult patients with the acute respiratory distress syndrome (ARDS) has focused on early intervention. A variety of approaches have been attempted using methods that modulate the components of the systemic inflammatory response, but none has led to a major breakthrough. However, early intervention is difficult to achieve for the majority of patients with ARDS who present with the syndrome fully established. Consequently, therapeutic approaches for rescue therapy also need to be developed. This requires a knowledge of events associated with progression and prognosis. The development of ARDS is characterized by damage to the pulmonary vascular endothelium.

Keywords

Lung Injury Acute Lung Injury Acute Respiratory Distress Syndrome Adult Respiratory Distress Syndrome Surfactant System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Science+Business Media Dordrecht 1996

Authors and Affiliations

  • Patricia L. Haslam

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