Epithelial Injury and Repair

  • Elizabeth L. Aronsen
  • John M. Shannon


Since the mid-1970s, increasing attention has been paid to the biological responses of alveolar epithelial type II cells following acute lung injury and their contribution to the syndrome of acute respiratory distress in adults (ARDS) [1]. Research has been greatly aided by techniques developed to isolate and culture type II cells in an environment separated from the complex milieu of the whole lung. In addition, application of molecular biological techniques to the study of these cells has rapidly expanded our understanding of the type II cell’s role in the structure and function of the alveolus, which will improve our knowledge of the mechanism by which a diverse group of risk factors can lead to the common final endpoint which is called ARDS, and may result in the development of specific therapies and interventions by which it can be treated [2,3].


Acute Lung Injury Alveolar Epithelial Cell Adult Respiratory Distress Syndrome Surfactant Protein Alveolar Type 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media Dordrecht 1996

Authors and Affiliations

  • Elizabeth L. Aronsen
  • John M. Shannon

There are no affiliations available

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