Lipid Feeding and Serum Esterases

  • Hein A. Van Lith
  • Bert F. M. Van Zutphen
  • Anton C. Beynen
Chapter
Part of the NATO ASI Series book series (NSSA, volume 266)

Summary

A brief review is given of the effects of the amount and type of dietary lipid on serum esterase activities in rabbits and selected rodent species. The feeding of a cholesterol-rich diet causes an increased activity of serum total esterase in rats, rabbits and mice. Cholesterol loading of rats, but not rabbits, lowers serum butyrylcholinesterase activity. The activity or level of a fast anodal serum esterase zone in rats (ES-1) and mice (ES-2) is raised after cholesterol feeding. The concentration and type of dietary fat influence ES-1 and total esterase activity in the serum of rats. Increased fat intakes markedly elevate serum ES-1 activity and slightly increase serum total esterase activity. The magnitude of this effect depends on the type of fat. In contrast to rats, the activity of an anodal fast moving serum esterase zone is decreased in gerbils after feeding a high-fat diet. Serum butyrylcholinesterase activities of rats and rabbits are slightly increased with increasing fat intakes. In gerbils, such an effect does not occur. Dietary fish oil when compared with either coconut fat, corn oil or olive oil produces increased activities of serum butyrylcholinesterase in rats.

Keywords

Esterase Activity Dietary Cholesterol Zealand White Rabbit Cholesterol Feeding Arylesterase Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Holmes, R.S., Masters, C.J. and Webb, E.C., A comparative study of vertebrate esterase multiplicity, Comp. Biochem. Physiol. 26, (1968), 837–852.PubMedCrossRefGoogle Scholar
  2. 2.
    Van Zutphen, L.F.M., Revision of the genetic nomenclature of esterase loci in the rat (Rattus norvegicus), Transplant. Proc. 5, (1983), 1687–1688.Google Scholar
  3. 3.
    Van Zutphen, L.F.M. and Den Bieman, M.G.C.W., Gene mapping and linkage homology, in: “New Developments in Biosciences: Their Implications for Laboratory Animal Science”, Beynen, A.C. and Solleveld, H.A., eds., Martinus Nijhoff Publishers, Dordrecht, (1988), 197–200.CrossRefGoogle Scholar
  4. 4.
    Williams, F.M., Clinical significance of esterases in man, Clin. Pharmacokinet. 10, (1985), 392–403.PubMedCrossRefGoogle Scholar
  5. 5.
    Reidenberg, M.M., The procaine esterase activity of serum from different mammalian species, Proc. Soc. Exp. Biol. Med. 140, (1972), 1059–1061.PubMedCrossRefGoogle Scholar
  6. 6.
    Van Zutphen, L.F.M. and Den Bieman, M.G.C.W., Genetic variation in hydrolysis of clofibrate, cyclaine and piperocaine in rabbit serum, IRCS Med. Sci. 6, (1978), 460.Google Scholar
  7. 7.
    Shirai, K., Ohsawa, J., Saito, Y. and Yoshida, S., Effects of phospholipids on hydrolysis of trioleoylglycerol by human serum carboxylesterase, Biochim. Biophys. Acta 962, (1988), 377–383.PubMedCrossRefGoogle Scholar
  8. 8.
    Tsujita, T. and Okuda, H., Carboxylesterases in rat and human sera and their relationship to serum aryl acylamidases and cholinesterases, Eur. J. Biochem. 133, (1983), 215–220.PubMedCrossRefGoogle Scholar
  9. 9.
    Lewis, A.A.M. and Hunter, R.L., The effect of fat ingestion on the esterase isozymes of intestine, intestinal lymph and serum, J Histochem. Cytochem. 14, (1966), 33–39.PubMedCrossRefGoogle Scholar
  10. 10.
    Wassmer, B., Augenstein, U., Ronai, A., De Looze, S. and Von Deimling, O., Lymph esterases of the house mouse (Mus musculus)-II. The role of esterase-2 in fat resorption, Comp. Biochem. Physiol. 91B, (1988), 179–185.CrossRefGoogle Scholar
  11. 11.
    Beynen, A.C., Weinans, G.J.B. and Katan, M.B., Arylesterase activities in the plasma of rats, rabbits and humans on low-and high-cholesterol diets, Comp. Biochem. Physiol. 78B, (1984), 669–673.Google Scholar
  12. 12.
    Beynen, A.C., Katan, M.B. and Van Zutphen, L.F.M. Plasma lipoprotein profiles and arylesterase activities in two inbred strains of rabbits with high or low response of plasma cholesterol to dietary cholesterol, Comp. Biochem. Physiol. 79B, (1984), 401–406.Google Scholar
  13. 13.
    Van Lith, H.A., Meijer, G.W., Haller, M. and Beynen, A.C., Serum pseudocholinesterase activity in rabbits fed simvastatin, Biochem. Pharm. 41, (1991), 460–461.PubMedCrossRefGoogle Scholar
  14. 14.
    Beynen, A.C., Lemmens, A.G., De Bruijne, J.J., Ronai, A., Wassmer, B., Von Deimling, O, Katan, M.B. and Van Zutphen, L.F.M., Esterases in inbred strains of mice with differential cholesterolemic responses to a high-cholesterol diet, Atherosclerosis 63, (1987), 239–249.PubMedCrossRefGoogle Scholar
  15. 15.
    Van Lith, H.A., Van Zutphen, L.F.M. and Beynen, A.C., Butyrylcholinesterase activity in plasma of rats and rabbits fed high-fat diets, Comp. Biochem. Physiol. 98A, (1991), 339–342.CrossRefGoogle Scholar
  16. 16.
    Van Lith, H.A., Meijer, G.W., Van Der Wouw, M.J.A., Den Bieman, M., Van Tintelen, G., Van Zutphen, L.F.M. and Beynen, A.C., Influence of amount of dietary fat and protein on esterase-1 (ES-1) activities of plasma and small intestine in rats, Br. J. Nutr. 67, (1992), 379–390.PubMedCrossRefGoogle Scholar
  17. 17.
    Van Lith, H.A., Haller, M., Van Tintelen, G., Van Zutphen, L.F.M. and Beynen, A.C., Plasma esterase-1 (ES-1) activity in rats is influenced by the amount and type of dietary fat, and butyryl cholinesterase activity by the type of dietary fat, J. Nutr. 122, (1992), 2109–2120.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1994

Authors and Affiliations

  • Hein A. Van Lith
    • 1
  • Bert F. M. Van Zutphen
    • 1
  • Anton C. Beynen
    • 1
  1. 1.Department of Laboratory Animal Science, Faculty of Veterinary MedicineUtrecht UniversityUtrechtThe Netherlands

Personalised recommendations