Urolithiasis pp 283-286 | Cite as

Ureaplasma Urealyticum: An Etiological Agent for the Development of Infection Stones in the Urinary Tract

  • L. Grenabo
  • H. Hedelin
  • S. Pettersson


Infection stones, composed of magnesium ammonium phosphate (struvite) and/or calcium phosphate are the second most common type of stone in the urinary tract in man (1). Urinary tract infection with urease-producing bacteria is considered a pre-requisite for the formation of these stones (2). The enzyme urease splits urea into ammonia and carbon dioxide. In the alkaline urine so formed, the formation products of struvite and calcium phosphate can be exceeded.


Urinary Tract Calcium Phosphate Stone Formation Bladder Stone Ureaplasma Urealyticum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    EL Prien and C Frandel, Studied in urolithiasis: 1. The composition of urinary calculi, J. Urol. 57: 949 (1947).PubMedGoogle Scholar
  2. 2.
    DP Griffith, Struvite stones, Kidney Int. 13: 372 (1978).PubMedCrossRefGoogle Scholar
  3. 3.
    RB Thompson and TA Stamey, Bacteriology in infection stones, Urol. 2: 627 (1973).PubMedCrossRefGoogle Scholar
  4. 4.
    HJE Lewi, A White, AG Hutchinson, and R Scott, The bacteriology of the urine and renal calculi, Urol. Res. 12: 107 (1984).PubMedCrossRefGoogle Scholar
  5. 5.
    L Grenabo, JE Brorson, H Hedelin, and S Pettersson, Ureaplasma urealyticum induced crystallization of magnesium ammonium phosphate and calcium phosphates in synthetic urine, J. Urol. 132: 795 (1984).PubMedGoogle Scholar
  6. 6.
    L Grenabo, JE Brorson, H Hedelin, and S Pettersson, Concrement formation in the urinary bladder in rats inoculated with Ureaplasma urealyticum. Urol. Res. 13: 195 (1985).PubMedCrossRefGoogle Scholar
  7. 7.
    L Grenabo, H Hedelin, and S Pettersson, Adherence of urease-indueed crystals to rat bladder epithelium following acute infection with different uropathogenic microorganisms, J. Urol. In press (1988).Google Scholar
  8. 8.
    MC Shepard and CD Lunceford, Urease color test medium U-9 for the detection and identification of “T” mycoplasmas in clinical material, Microbiology (Suppl.) 20: 539 (1970).Google Scholar
  9. 9.
    MS Spaepen, RB Kundsin, and HW Home, Tetracycline-resistant T-Mycoplasmas (Ureaplasma urealyticum) from patients with history of retroproductive failure, Antimicrob. Agents Chemother. 9: 1012 (1976).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • L. Grenabo
    • 1
  • H. Hedelin
    • 1
  • S. Pettersson
    • 1
  1. 1.Department of UrologySahlgrenska sjukhusetGöteborgSweden

Personalised recommendations