Renal Functional Alterations after Extracorporeal Shock-Wave Lithotripsy Assessed by Measurement of Urinary Proteins
Currently, extracorporeal shock-wave lithotripsy (ESWL) is the method of choice for treatment of renal and ureteral calculi. From various animal experiments, it is known that renal damage can occur when large doses of these high-energy pressure waves are directed towards the kidney. On the other hand, routine treatment does not seem to jeopardize renal function too much. In approximately 1% of the patients, perirenal or intrarenal hematomas lead to clinical symptoms. It has been difficult to quanititative-ly assess renal damage after ESWL. Imaging techniques like axial computerized tomography or nuclear scans can show morphological changes only after ESWL, such as diminished perfusion or perirenal fluid collection of edema of the kidney in 30 to 50%. However, radionuclide scans do not show these alterations regularly.