Urolithiasis pp 617-617 | Cite as

Effect of Hypovitaminosis A and Supplementation of Vitamin D3 on Calcium and Oxalate Absorption by Rat Intestinal Brush-Border-Membrane Vesicles

  • S. Sharma
  • R. Narula
  • H. Sidhu
  • S. K. Thind
  • R. Nath

Abstract

Urolithiasis as a complication of gastrointestinal disorders is well recognized. Vitamin A deficiency is implicated as a possible etiological factor for stone formation and is known to affect the epithelia of the gastrointestinal, urogenital, and respiratory tracts. Therefore, the biochemical changes produced by vitamin-A deficiency on intestinal absorption of calcium and oxalate by brush-border-membrane vesicles (BBMV) was studied. The intestinal BBMV were prepared by differential centrifugation, and uptake of calcium and oxalate was studied by a rapid filtration technique (1).

Keywords

Retinoic Acid Calcium Uptake Stone Formation Brush Border Membrane Oxalate Absorption 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    U Hopfer, K Nelson, J Perotto, and KJ Isselbacher, Glucose transport in isolated brush border membrane from rat small intestine, J. Biol. Chem. 248: 25 (1973).PubMedGoogle Scholar
  2. 2.
    U Trechsel and H Fleisch, Retinol and retinoic acid modulate the metabolism of 25 hydroxyvitamin D3 in kidney cell culture, FEBS Letters 135: 115 (1981).PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • S. Sharma
    • 1
  • R. Narula
    • 1
  • H. Sidhu
    • 1
  • S. K. Thind
    • 1
  • R. Nath
    • 1
  1. 1.Department of BiochemistryPostgraduate Institute of Medical Education and ResearchChandigarhIndia

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