Urolithiasis pp 479-479 | Cite as

Mitochondrial and Cellular Metabolism in Experimental Hyperoxaluric Nephrolithiasis

  • M. Menon
  • T. Strzelecki
  • B. McGraw
  • C. Scheid

Abstract

We have speculated that calcium-oxalate nephrolithiasis results from a combination of two distinct processes - tubular cell dysfunction and calcium/oxalate hyper-excretion. To test this hypothesis, we investigated whether oxalate overload by itself would give rise to cellular derangements by assessing cellular and mitochondrial function in an animal model of nephrolithiasis characterized by profound hyperoxaluria.

Keywords

Mitochondrial Function Ammonium Chloride Distinct Process Renal Calculus Tubular Damage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • M. Menon
    • 1
  • T. Strzelecki
    • 1
  • B. McGraw
    • 1
  • C. Scheid
    • 1
  1. 1.University of Massachusetts Medical CenterWorcesterUSA

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