The Effect of Increasing Urate Concentration on the Precipitation of Calcium Oxalate from Human Urine
The role of urate in calcium oxalate (CaOx) urolithiasis remains polemic. In 1970, Kallistratos et al. (1) reported that addition of urate to the urine’ salted out’ CaOx, a finding that has been largely ignored despite its potential significance in CaOx stone formation. The aim of this study was to examine the effect of dissolved urate, at physiological concentrations, on the metastable limit of human urine, and to characterize the crystalline material deposited after induction of CaOx crystallization.
KeywordsHuman Urine Crystalline Material Calcium Oxalate CaOx Crystal Control Urine
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