Urolithiasis pp 461-463 | Cite as

The Effect of Increasing Urate Concentration on the Precipitation of Calcium Oxalate from Human Urine

  • P. K. Grover
  • R. L. Ryall
  • V. R. Marshall

Abstract

The role of urate in calcium oxalate (CaOx) urolithiasis remains polemic. In 1970, Kallistratos et al. (1) reported that addition of urate to the urine’ salted out’ CaOx, a finding that has been largely ignored despite its potential significance in CaOx stone formation. The aim of this study was to examine the effect of dissolved urate, at physiological concentrations, on the metastable limit of human urine, and to characterize the crystalline material deposited after induction of CaOx crystallization.

Keywords

Human Urine Crystalline Material Calcium Oxalate CaOx Crystal Control Urine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    G Kailistratos, A Timmermann, and O Fenner, Zum einfluss des ausselzeffktes auf die bildung von calciumoxalat-kristallen im menslichen harn, Naturwissenschaften 57: 198 (1970).CrossRefGoogle Scholar
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    WG Robertson, F Knowles, and M Peacock, Urinary mucopolysaccharide inhibitors of calcium oxalate crystallization, in: “Urolithiasis Research,” H Fleisch, WG Robertson, LH Smith, and W Vahlensieck, eds., Plenum Press, New York (1976).Google Scholar

Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • P. K. Grover
    • 1
  • R. L. Ryall
    • 1
  • V. R. Marshall
    • 1
  1. 1.Urology Unit, Department of SurgeryFlinders Medical CenterBedford ParkSouth Australia

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