Urolithiasis pp 443-445 | Cite as

Oxalate Exchange in Red Blood Cells of Calcium-Oxalate Stone Formers: A Pharmacological Study

  • S. Cantaro
  • F. Marchini
  • L. Calò
  • G. Gambaro
  • A. Piccoli
  • H. E. Williams
  • B. Baggio
  • A. Borsatti

Abstract

We have previously presented data demonstrating that oxalate selfexhange in red blood cells (RBC) of renal stone formers occurs more rapidly than normal (1). We also have evidence that the anomaly resides in band 3 protein, the anion exchanger (1), and is in some way related to the degree of phosphorylation of the protein (2).

Keywords

Erythrocyte Membrane Protein cAMP Synthesis Specific Protein Kinase Calcium Nephrolithiasis Redundant Control 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    B Baggio, G Gambaro, F Marchini, E Ciceriello, R Tenconi, M Clementi, and A Borsatti, An inheritable anomaly of red-cell oxalate transport in “primary” calcium nephrolithiasis correctable with diuretics, NEJM 314: 599 (1986).PubMedCrossRefGoogle Scholar
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    B Baggio, G Clari, G Marzaro, G Gambaro, A Borsatti, and V Moret, Erythrocyte membrane protein phosphorylation in urolithiasis, Contr. Nephrol. 58: 156 (1987).Google Scholar
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    KB Seamon and JW Daly, Forskolin: a unique diterpene activator of cyclic AMP-generating systems, J. Cyclic Nucleotide Res. 7: 201 (1981).PubMedGoogle Scholar
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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • S. Cantaro
    • 1
  • F. Marchini
    • 1
  • L. Calò
    • 1
  • G. Gambaro
    • 1
  • A. Piccoli
    • 1
  • H. E. Williams
    • 2
  • B. Baggio
    • 1
  • A. Borsatti
    • 1
  1. 1.Institute of Internal Medicine, Division of NephrologyUniversity of PadovaPadovaItaly
  2. 2.University of California School of MedicineDavisUSA

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