Seasonal Variations in Urinary Crystalluria and Glutamate Transaminase Levels in Stone Formers and Healthy Normal Subjects
Urinary crystals are considered to be microliths because at any time they can grow into uroliths when conditions are favourable. A more intense and higher prevalence of crystalluria is reported in stone formers (SF) in the summer season as compared to winter (1). Two explanations have been given for this: first, the urine is saturated in summer; and second, there are lower levels of glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) at this time. These enzymes are important since they decrease the glutamic acid level in urine and act as inhibitors. In the present study, we have examined the urinary crystalluria, GOT, and GPT levels in summer (37–39°C) and in winter (5–19°C).