Urolithiasis pp 379-382 | Cite as

Premature Infants Treated with Furosemide have Increased Urinary Calcium and Unchanged Urinary Citrate Excretion Compared to Controls

  • N. D. Adams
  • J. C. Rowe
  • R. X. Liu
  • R. Sawhney
  • A. M. Lazar
  • E. Horak
  • S. D. Hopfer
  • T. B. Condren

Abstract

Nephrocalcinosis (NC) is a frequent complication in very low birth weight (VLBW, <1500 g) infants who are treated with furosemide (F) for bronchopulmonary dysplasia (BPD). Since most infants treated with F become hypercalciuric, yet only half develop NC, factors other than calcium excretion must contribute to the development of this disorder. We postulate that citrate excretion which appears to be under developmental control, may be one of these factors.

Keywords

Premature Infant Calcium Oxalate Bronchopulmonary Dysplasia Renal Tubular Acidosis Ethacrynic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1989

Authors and Affiliations

  • N. D. Adams
    • 1
  • J. C. Rowe
    • 1
  • R. X. Liu
    • 1
  • R. Sawhney
    • 1
  • A. M. Lazar
    • 1
  • E. Horak
    • 1
  • S. D. Hopfer
    • 1
  • T. B. Condren
    • 1
  1. 1.Departments of Medicine, Pediatrics, and Laboratory MedicineThe University of Connecticut Health CenterFarmingtonUSA

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