Intestinal Absorption of Epidermal Growth Factor in Newborn Lambs
Milk contains high concentrations of numerous growth factors including epidermal growth factor (EGF)1 and insulin-like growth factor-1 (IGF-1)2,3,4, observations that have led to the suggestion that milk growth factors may play an important role in infant growth and development.1,4 This would be possible only if growth factors survive digestion in the neonatal gastrointestinal tract. Moreover, direct actions on tissues other than the gut mucosa would further require that substantial amounts of milk growth factors are absorbed intact into the neonatal circulation.
KeywordsHuman Milk Blood Flow Rate Bovine Colostrum Newborn Lamb Epidermal Growth Factor Concentration
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