In most textbooks, infectious mononucleosis is described as a self-limited acute illness lasting 2 to 3 weeks. In the vast majority of patients, recovery occurs uneventfully without specific therapy. Recurrent and chronic forms of the illness are not described in textbooks, although a more gradual resolution of the illness has been noted. Recently, on television, in newspapers, and in numerous popular magazines, an illness called chronic Epstein—Barr virus (CEBV), or the “yuppie flu” because it often attacks better-educated, hard-driving, young professionals, has been described. This has been called by some writers as “the malaise of the 80s” and support groups have sprung up throughout this and other countries round the world. The practicing clinician has been besieged by patients seeking elief for this illness with little guidance from the usual medical sources. This has been an extremely frustrating situation for both patients and clinicians.
KeywordsChronic Fatigue Syndrome Infectious Mononucleosis Royal Free Hospital Unexplained Fatigue Unexplained Chronic Fatigue
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