Morphological Characterization of ALZ-50 Immunoreactive Cells in the Developing Neocortex of Kittens
Alz-50 is a monoclonal antibody isolated from brain tissue of patients with Alzheimer’s disease (Wolozin et al., 1986). This antibody recognizes an antigenic protein of 68 kilodaltons in neurons involved in the formation of neuritic plaques and neurofibrillary tangles. It has been reported recently that Alz-50 immunoreactive (ir) neurons are found in normal fetal and neonatal human brains and in brain tissue from neonatal individuals with Down’s syndrome (Wolozin et al., 1988).
KeywordsWhite Matter Visual Cortex Down Syndrome Neurofibrillary Tangle Senile Plaque
Unable to display preview. Download preview PDF.