Pharmacological Agents and the Release of Arachidonic Acid and Prostaglandin Biosynthesis by Rabbit Iris Muscle

  • Ata A. Abdel-Latif
  • Shokofeh Naderi
  • Sardar Y. K. Yousufzai
Part of the FIDIA Research Series book series (FIDIA, volume 4)

Abstract

Arachidonic acid (AA), the precursor of prostaglandins (PGs) and other biological active substances, is found mainly esterified to membrane phospholipids, almost exclusively in the 2-acyl position, from which it could be released by the action of lipases (Lands and Samuelson, 1968; Vogt, 1978) and reincorporated by a deacylation-reacylation cycle (for reviews see Hill and Lands, 1970; Holub and Kuksis, 1978; Irvine, 1982).

Keywords

Arachidonic Acid Arachidonic Acid Release Myoinositol Phosphate Rabbit Iris Iris Muscle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

PG

prostaglandin

PAF

platelets-activating factor

NE

norepinephrine

DG

1, 2-diacylglycerol

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • Ata A. Abdel-Latif
    • 1
  • Shokofeh Naderi
    • 1
  • Sardar Y. K. Yousufzai
    • 1
  1. 1.Department of Cell and Molecular BiologyMedical College of GeorgiaAugustaUSA

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