Hydration of DNA and Possible Role of Water in the Transition between Right- and Left-Handed Double Helix

  • G. M. Mrevlishvili
  • G. Sh. Japaridze
  • V. M. Sokhadze
  • Z. I. Chanchalashvili
  • D. A. Tatishvili

Abstract

As we already know from the classical X-ray studies, the conformation of DNA double helix depends to a great extent on water and different cation content[1,2]. Unfortunately, until now we have been forced to consider structural parameters of DNA molecules only in terms of spatial molecular models[3]. Only recently a noticeable progress has been made in this field[4–10]. The obtained data show[5] that structural and dynamic properties of polynucleotide chains with definite nucleotide sequence lead to the forms of double helix radically differing from B-DNA conformation. We are considering so-called Z-DNA, or left handed DNA with the structure determined on the basis of X-ray analysis of monocrystals of oligonucleotides with alternating pur-pyr sequences[4–7].

Keywords

Double Helix Excess Heat Capacity Eutectic Melting Mixture Melting Polynucleotide Chain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1985

Authors and Affiliations

  • G. M. Mrevlishvili
    • 1
  • G. Sh. Japaridze
    • 1
  • V. M. Sokhadze
    • 1
  • Z. I. Chanchalashvili
    • 1
  • D. A. Tatishvili
    • 1
  1. 1.Institute of PhysicsAcademy of Sciences of the Georgian USSRTbilisiUSSR

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