Taurine 2 pp 51-53 | Cite as

Taurine Administration Raises Plasma Taurine Levels and Affects Certain Plasma Amino Acids and Related Compounds in Rats

  • Karsten Korang
  • Louis Milakofsky
  • Theodor A. Hare
  • James M. Hofford
  • Wolfgang H. Vogel
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 403)

Abstract

In spite of the interest in the pharmacology of taurine, little information is available on its absorption into the blood stream after administration to the rat. For this reason, we conducted a pharmacokinetic study on the fate of injected taurine in rat plasma for 4 h and measured its effects on a large number of plasma amino acids and related compounds.

Keywords

Amino Acid Level Increase Plasma Level Plasma Amino Acid Amino Compound Free Amino Acid Content 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Fukuda, K. and Usui, T. 1983, Characteristic patterns of free amino acid content in plasma, erythrocytes, lymphocytes, and granulocytes in man, Hiroshima J. Med. Sci., 32:163–166.Google Scholar
  2. 2.
    Huxtable, R.J. 1992, Physiological Actions of Taurine, Physiol. Rev. 72:101–163.Google Scholar
  3. 3.
    Milakofsky, L., Hare, T.A., Miller, J.M. and Vogel, W.H. 1983, Comparison of amino acid levels in rat blood obtained by decapitation or catherization, Life Sci., 34:1333–1340.CrossRefGoogle Scholar
  4. 4.
    Paauw, J.D. and Davis, T.A. 1990, Taurine supplementation at three different dosages and its effect on trauma patients, Am. J. Nutr., 60:203–206.Google Scholar

Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Karsten Korang
    • 1
  • Louis Milakofsky
    • 1
    • 2
  • Theodor A. Hare
    • 1
  • James M. Hofford
    • 3
  • Wolfgang H. Vogel
    • 1
  1. 1.Departments of Pharmacology and Psychiatry and Human BehaviorJefferson Medical College of Thomas Jefferson UniversityPhiladelphiaUSA
  2. 2.Department of ChemistryPenn State University, Berks CampusReadingUSA
  3. 3.Department of MedicineJefferson Medical College of Thomas Jefferson UniversityPhiladelphiaUSA

Personalised recommendations