Infection of Human Dendritic Cells by Measles Virus Induces Immune Suppression
Measles is characterized by lifelong immunity and a transient immunosuppression which, in developing countries, is responsible for a high morbidity and a high mortality consecutive to secondary infections. Strickingly, the immune suppression is coincident with MV-specific immunity and continues for several weeks after apparent recovery from measles. The immune suppression is characterized by the loss of delayed-type hypersensitivity skin test responses to recall antigens, such as tuberculin, and by the inhibition of antibody production and cellular immune responses to new antigens (1).
KeywordsImmune Suppression Measle Virus Human Dendritic Cell Measle Virus Infect Skin Test Response
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