Functional Role of CD101 on Skin Dendritic Cells

  • Martine Bagot
  • Isabelle Martinel
  • Dominique Charue
  • Marie-Laure Boulland
  • Janine Wechsler
  • Armand Bensussan
  • Laurence Boumsell
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 417)

Abstract

CD101 is a cell surface protein with a molecular weight of about 140 kDa and seven Ig-like loops in its extra-cellular domain, that was first described in our laboratory, using two different monoclonal antibodies (mAb), BB27 and BA27 (1,2). The two anti-CD101 mAbs BB27 and BA27 were generated by immunization of BALB/c mice with the CD4+CD8+ thymic clone B12 (3). These mAbs recognize CD101, a disulfide bonded-homodimer, on subsets of circulating T lymphocytes.

Keywords

Costimulatory Molecule Skin Explants Human Skin Explants Skin Dendritic Cell Cutaneous Dendritic Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1997

Authors and Affiliations

  • Martine Bagot
    • 1
  • Isabelle Martinel
    • 1
  • Dominique Charue
    • 1
  • Marie-Laure Boulland
    • 2
  • Janine Wechsler
    • 2
  • Armand Bensussan
    • 1
  • Laurence Boumsell
    • 1
  1. 1.INSERM U448, IM3Paris XII University Hôpital Henri MondorCréteilFrance
  2. 2.Department of PathologyParis XII University Hôpital Henri MondorCréteilFrance

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