The Transdermal Route for the Delivery of Peptides and Proteins

  • B. W. Barry
Part of the NATO ASI Series book series (NSSA, volume 125)

Abstract

Little work has been reported in the literature on the percutaneous delivery of peptides and proteins. This chapter therefore aims to survey the problems associated with the use of the intact skin as a pathway of entry of drugs into the systemic circulation, and to attempt to predict some of the difficulties likely to arise if the penetrants are peptides. However, at the outset we can deduce with some confidence that the efficient, controlled delivery of intact peptides and proteins to the systemic circulation via the transdermal route will prove to be the most challenging project to date in skin permeation technology.

Keywords

Stratum Corneum Hair Follicle Sweat Gland Sebaceous Gland Percutaneous Absorption 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1986

Authors and Affiliations

  • B. W. Barry
    • 1
  1. 1.Postgraduate School of PharmacyUniversity of BradfordBradfordUK

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