Introduction: Role of Potassium in Exercise Hyperpnoea
It is generally accepted that ventilation (̇VE) in exercise is regulated by a combination of neural and chemical drives, but the exact nature and relative contributions of the controlling signals are not agreed upon. Current thinking suggests that this control is based on a high degree of redundancy so that no single factor is responsible1. Recently, attention has focused on the idea that a substance that is released from exercising muscle2, 3 may contribute significantly to this control. This chapter examines evidence4, 5 which suggests that potassium fulfils the criteria of being a work substance and, that it stimulates ̇VE in exercise by increasing the sensitivity of the arterial chemoreflex.
KeywordsCarotid Body Ventilatory Response Glycogen Depletion Incremental Exercise Test Arterial Chemoreceptor
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