Comparative Hemostasis

  • Jessica H. Lewis

Abstract

The bleeding time is the time measured with a stopwatch between the making of a small incision in the skin and the moment the bleeding stops. Duke in 1910 was the first to describe, in humans, a bleeding time involving a cut on the fingertip or earlobe. Ivy in 1941 standardized the procedure to the making of a shallow cut with a new knife blade on the ventral surface of the forearm with a sphygmomanometer cuff on the upper arm inflated to 30–40 mm Hg. Mielka et al. (1969) developed a template to standardize the length and depth of the cut. Currently, most bleeding times done in humans involve a perpendicular cut on the cleaned volar surface of the forearm in an area without visible veins. A commercially available template, Simplate (OT), is most frequently used.

Keywords

Factor VIII Bleeding Time Thrombin Time Generate Mixture Clot Retraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1996

Authors and Affiliations

  • Jessica H. Lewis
    • 1
  1. 1.University of Pittsburgh School of Medicine and Central Blood BankPittsburghUSA

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