At this point I have established that cholesterol is subject to insidious autoxidation under relatively mild conditions. It is essential to continued progress in the study of cholesterol that this fact not be ignored, as cholesterol autoxidation products may confound analyses and obscure details of sterol metabolism. The matter is all the more important as it is now certain that cholesterol autoxidation products exert divers deleterious biological actions in select test systems and may play a role in regulation of endogeneous metabolism and etiology of disease.
KeywordsSteryl Ester High Performance Liquid Column Chromatography Autoxidation Product Chemical Ionization Mass Spectrum Proton Nuclear Magnetic Resonance Spectrum
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