The Influence of the Hematopoietic System on the Production of MHC-Related Odors in Mice

  • Dagmar Luszyk
  • Frank Eggert
  • Lutz Uharek
  • Wolfgang Muller-Ruchholtz
  • Roman Ferst

Abstract

Yamazaki et al. (1985) were able to demonstrate an influence of the hematopoietic system on H-2-associated urine odors. H-2 is the designation of the major histocompatibility complex (MHC) of the mouse and is located on chromosome 17. The MHC was originally identified by its role in transplant rejection, but it is now recognized that proteins encoded in this region are involved in many aspects of immunological recognition. H-2 congenic imbred mice differ genetically only in the H-2 but not in the rest of their genomes, syngeneic mice share both haplotypes of the H-2, and semiallogeneic share one of the two haplotypes of the H-2.

Keywords

Major Histocompatibility Complex Bone Marrow Transplantation Inbred Strain Transplant Rejection Hematopoietic System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Eggert, F., Luszyk, D., Ferstl, R. and Muller-Ruchholtz, W., 1989, Changes in strain-specific urine odors of mice due to bone marrow transplantations, Neuropsychobiology, 22: 57.PubMedCrossRefGoogle Scholar
  2. Ferstl, R., Welzel, C., Florian, M., Blank, M. and Muller-Ruchholtz, W., 1988, Ist das Knochenmark der einzige Ursprung korpereigener Duftkomponenten? Z. Exp. Angew. Psychol., 35: 201.PubMedGoogle Scholar
  3. Luszyk, D., Eggert, F., Ferstl, R., Blank, M., and Muller-Ruchholtz, W., 1989, Der Austausch des hamatopoetischen Systems verandert die chemosensorische Identitat, Z. Exp. Angew. Psychol., 36: 239.PubMedGoogle Scholar
  4. Luszyk, D., Eggert, F., Ferstl, R., Blank, M., and Muller-Ruchholtz, W., 1990, Exchange of the hematopoietic system alters the chemosensory identity, German J. Psychol., 14: 27.Google Scholar
  5. Muller-Ruchholtz,W., Wottage, H.-U. and Muller-Hermelink, H.K, 1980, Restitution potentials of allogeneically or xenogeneically grafted lymphocyte-free hematopoietic stem cells, in: “Immunobiology of Bone Marrow Transplantation”, S. Thierfelder, H. Rodt, H.J. Kolb, eds., Springer, Berlin.Google Scholar
  6. Sobottka, B., Eggert, F., Ferstl, R. and Muller-Ruchholtz, W., 1990, Altered chemosensory identity after experimental bone marrow transplantation: Recognition by another species, German J. Psychol., 14: 213.Google Scholar
  7. Yamazaki, K., Beauchamp, G.K., Thomas, L., Boyse, E.A., 1985, The hema topoietic system is a source of odorants that distinguish major histocompatibility types, J. Exp. Med., 162: 1377.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Dagmar Luszyk
    • 1
  • Frank Eggert
    • 1
  • Lutz Uharek
    • 2
  • Wolfgang Muller-Ruchholtz
    • 2
  • Roman Ferst
    • 1
  1. 1.Department of PsychologyUniversity of KielKielGermany
  2. 2.Department of ImmunologyUniversity of KielKielGermany

Personalised recommendations