Additive Effect of Low-Dose Diethylnitrosamine on the Initiation of Liver Carcinogenesis in Rats
Simultaneous or exposure to low-dose carcinogens existing in the environment is an important causal factor in human carcinogenesis. It is gener- ally accepted that carcinogenesis is a multi-step process consisting of two qualitatively different stages, initiation and promotion1. Initiation is a transient “flash” phenomenon involving exposure to a carcinogen and may occur frequently in humans.
KeywordsPartial Hepatectomy Experimental Regimen Liver Carcinogenesis Experimental Schedule Important Causal Factor
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