Cell Fusion pp 441-456 | Cite as

Micromanipulation and Elastic Response of Electrically Fused Red Cells

  • Donna M. Miles
  • Robert M. Hochmuth

Abstract

Fusion of human erythrocytes may be obtained by several methods such as incubation with uranyl ions or some rare earth metals (Majumdar etal., 1980), treatment with calcium and phosphate ions (Baker and Kalra, 1979), incubation with viral fusogens such as the Sendai virus (Knutton, 19796), and treatment with polyethylene glycol (Knutton, 1979a). The method of electrofusion is relatively new in comparison and in its early stages of investigation and application. According to Zimmermann and Vienken (1982), electrofusion has several advantages compared with other methods of fusion: (1) the number of cells to be fused may be selected, (2) the loss of intracellular contents is decreased, and (3) the membrane properties are not changed by the addition of other substances.

Keywords

Alternate Current Direct Current Pulse Aspiration Pressure Cell Doublet Alternate Current Field 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Donna M. Miles
    • 1
  • Robert M. Hochmuth
    • 1
  1. 1.Department of Biomedical EngineeringDuke UniversityDurhamUSA

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